| 产品编号 |
bs-41452P |
| 英文名称 |
Recombinant SARS-Cov-2 N protein (D3L, P13T, D103Y, D128Y, H145Y, R203K, G204R, T205I, S235F), His
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| 中文名称 |
重组SARS冠状病毒核衣壳突变蛋白(D3L,P13T,D103Y,D128Y,H145Y,R203K,G204R,T205I,S235F), His tag, (南非) |
| 别 名 |
SARS-CoV-2 Nucleocapsid Protein; SARS-CoV-2 NP; nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2]; novel coronavirus N Protein; novel coronavirus Nucleocapsid Protein; 2019-nCoV Nucleoprotein; 2019-nCoV N; 2019nCoV N; 2019-nCoV N Prot 突变型新冠蛋白; 新冠病毒N蛋白突变体（D3L,P13T,D103Y,D128Y,H145Y,R203K,G204R,T205I,S235F）; 重组新冠病毒核衣壳突变蛋白(D3L,P13T,D103Y,D128Y,H145Y,R203K,G204R,T205I,S235F); 新型冠状病毒核衣壳突变体蛋白. |
| 理论分子量 |
46 kDa |
| 检测分子量 |
50 |
| 性 状 |
Lyophilized or Liquid |
| 浓 度 |
＞0.5 mg/ml |
| 物 种 |
SARS-Cov-2 |
| 序 列 |
1-419/419 |
| 纯 度 |
>90% as determined by SDS-PAGE |
| 纯化方法 |
AC |
| 内毒素 |
Not analyzed |
| 表达系统 |
E.coli |
| 活性 |
Not tested |
| 标签 |
His |
| 缓 冲 液 |
20mM Tris-HCl (pH8.0) with 500mM NaCl. |
| 保存条件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
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| 产品图片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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